I've not had any of the reported issues so far. While the original Mavericks release ran noticeably slower than Mtn Lion, after the first .x update, all has been well for me. Adobe apps were updated shortly after the Mavericks release, so they've been running great as well.
I say that knowing that I'm running Mavericks on desktop hardware that is either brand new or almost brand new models w/fully upgraded RAM, video cards and SSD drives.
However my laptop is a 2011 MBAir - and it runs Mavs just fine with only 4GB of RAM. I would guess however, that most hardware older than 2012 suffer some slow-downs and instability with Mavs.
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At this point, I'm going to wait for the .4 or .5 update, and then, instead of updating the OS over my current system, I'll completely wipe the drive and do a fresh reinstall of everything. At least, now that this will not be my primary working system (with the new gig starting next week), if it's still problematic, I won't have to worry a/b Workflow Interruptus.
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