I think that there have been great strides in the last decades in regards to auto safety... better seat belts, ABS, stricter child seat laws, crumple zones, reinforced doors, airbags.
Same with drinking and driving... more awareness, stricter laws, free rides from Taxis, designated drivers, organizations like MADD and such. There has been a monumental effort and failure when it come to drugs.

What have we seen in the weapons arena that has made great strides? Trigger locks.
And I don't own a gun... so anyone jump in with other efforts, inventions, laws.
And, mind you... this is the one that was designed to kill.... unlike autos.