WMD is often referred to by the collection of modalities that make up the set of weapons: chemical, biological, radiological, nuclear, and explosive (CBRNE). These are weapons that have a relatively large-scale impact on people, property, and/or infrastructure.
Interesting -- the first part of that definition includes:
"Weapons of Mass Destruction (WMD) are defined in US law (18 USC §2332a) as:
“(A) any destructive device as defined in section 921 of this title (i.e. explosive device);"
And according to section 921:
"(4) The term “destructive device” means—
(A) any explosive, incendiary, or poison gas— (i) bomb, (ii) grenade, (iii) rocket having a propellant charge of more than four ounces, (iv) missile having an explosive or incendiary charge of more than one-quarter ounce, (v) mine, or (vi) device similar to any of the devices described in the preceding clauses;
(B) any type of weapon (other than a shotgun or a shotgun shell which the Attorney General finds is generally recognized as particularly suitable for sporting purposes) by whatever name known which will, or which may be readily converted to, expel a projectile by the action of an explosive or other propellant, and which has any barrel with a bore of more than one-half inch in diameter; and
(C) any combination of parts either designed or intended for use in converting any device into any destructive device described in subparagraph (A) or (B) and from which a destructive device may be readily assembled."
So the range goes from anything above a .50 caliber gun to a nuke -- kind of broad definition of "weapon of mass destruction" given the hysteria surrounding the term. I would have thought the definition to be far more limited to weapons having really, really massive and devastating potential (ex: a small nuke vs., like, a hand grenade) ...
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