First you'll have to find out the interface... is it usb? if so, then you'll probably have to write some scripts to control the cursor and scrolling on screen using the click wheel. the center button can obviously be used for clicking... the four "corner" buttons can launch several actions... perhaps make it context dependant?!?!?!?

There's tremendous potential for a click wheel in audio and video editing aplication... give it a shot and keep us posted!!!!